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A new polymorphism (N21D) in the exon 2 of the human MDR1 gene encoding the P-glycoprotein

✍ Scribed by Xavier Declèves; Sylvie Chevillard; Charlotte Charpentier; Philippe Vielh; Jean-Louis Laplanche


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
11 KB
Volume
15
Category
Article
ISSN
1059-7794

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✍ Marie-Laure Kottler; Jean Pierre Lagarde; Karin Dahan; Leila Zekraoui; Alain Rai 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 41 KB 👁 1 views

Using DNA sequencing of the coding and exon flanking regions of the low density lipoprotein receptor (LDLR) gene we identified an Alw26 I site in exon 10 by a transition G1426A. The alleles are represented by one uncut fragment (A1 = 108 bp) or two fragments (A2 = 82bp and 26 pb). Two other fragment