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Expression of the Epstein-Barr Virus Immediate Early Gene, BZLF1, in Nasopharyngeal Carcinoma Tumor Cells

✍ Scribed by Chantal Cochet; Dominique Martel-Renoir; Virginie Grunewald; Jacques Bosq; Gilles Cochet; Guy Schwaab; Jean-François Bernaudin; Irène Joab


Book ID
112269436
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
698 KB
Volume
197
Category
Article
ISSN
0042-6822

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The ability of the Epstein-Barr virus (EBV) to avoid lytic replication and to establish a latent infection in B-lymphocytes is fundamental for its lifelong persistence and the pathogenesis of various EBV-associated diseases. The viral immediate-early gene BZLF-1 plays a key role for the induction of