Expression of the constitutively activated RelA/NF-κB in human astrocytic tumors and the in vitro implication in the regulation of urokinase-type plasminogen activator, migration, and invasion
✍ Scribed by Keishi Tsunoda; Gaspar Kitange; Takeo Anda; Hamisi Kimaro Shabani; Makio Kaminogo; Shobu Shibata; Izumi Nagata
- Book ID
- 106246142
- Publisher
- Springer Japan
- Year
- 2005
- Tongue
- English
- Weight
- 796 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1433-7398
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The urokinase-type plasminogen activator (uPA) and its receptor (uPAR) play an important role in tumour invasion. Previous studies have shown by RT-PCR that uPA and uPAR mRNAs are expressed in human hepatocellular carcinoma (HCC). Here, in situ hybridization, immunohistochemistry, and double immuno¯