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Expression of short-form caspase 8 correlates with decreased sensitivity to Fas-mediated apoptosis in neuroblastoma cells

✍ Scribed by Rodrick R. Kisenge; Hidemi Toyoda; Jian Kang; Shigeki Tanaka; Hatsumi Yamamoto; Eiichi Azuma; Yoshihiro Komada


Book ID
108582313
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
504 KB
Volume
94
Category
Article
ISSN
1347-9032

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Apoptosis induced by effector cells of the immune system or by cytotoxic drugs is a main mechanism mediating the prevention or elimination of tumoral cells. For instance, the human T-cell leukemia Jurkat is sensitive to Fas-induced apoptosis and to activation-induced cell death (AICD), and the promo