## Abstract Runt domain transcription factors are important targets of TGFβΞ² superfamily proteins and play a crucial role in mammalian development. Three mammalian runtβrelated genes, __RUNX1__, __RUNX2__ and __RUNX3__, have been described. __RUNX3__ has been shown to be a putative tumor suppressor
β¦ LIBER β¦
Expression of RUNX3 in skin cancers
β Scribed by J. H. Lee; J.-K. Pyon; D. W. Kim; S. H. Lee; H. S. Nam; S. G. Kang; C. H. Kim; Y. J. Lee; J. S. Chun; M. K. Cho
- Book ID
- 108696949
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 479 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0307-6938
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## Abstract The reputation of RUNX3 as a strong candidate for a tumor suppressor originated from studies of gastric carcinogenesis and now extends to a variety of other human cancers. The RUNX3 transcription factor is a downstream effector of the TGFβΞ² superfamily signaling pathway and has a critic
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