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Expression of Recombinant Human Methylmalonyl-CoA Mutase: In Primary mut Fibroblasts and Saccharomyces cerevisiae

✍ Scribed by E. Andrews; R. Jansen; A.M. Crane; S. Cholin; D. Mcdonnell; F.D. Ledley


Book ID
112237928
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
487 KB
Volume
50
Category
Article
ISSN
0885-4505

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We have examined the effect of addition of hydroxocobalamin to growth medium on the activity of the adenosylcobalamin-requiring enzyme methylmalonyl CoA mutase in normal human fibroblasts and in mutant human fibroblasts derived from patients with inherited methylmalonicacidemia. The mutant cell line