## Abstract Prostate specific membrane antigen (PSMA) is a folate Ξ³ glutamyl carboxypeptidase that is oriented on the plasma membrane of normal and prostate cancer cells. A cytosolic version of PSMA, PSMβ², results from alternative splicing of the PSMA gene. Two additional alternatively spliced vari
Expression of prostate-specific antigen in human prostate specimens in in vitro three-dimensional histoculture
β Scribed by Jack Geller; Lida Sionit; Kenneth Connors; Tyler Youngkin; Robert M. Hoffman
- Book ID
- 112803519
- Publisher
- Society for In Vitro Biology
- Year
- 1993
- Tongue
- English
- Weight
- 231 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1475-2689
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The authors thank Liisa Kaarela, Helmi Konola, and Mirja Ma Β¨kela Β¨inen for their expert technical assistance and Risto Bloigu for helping with the statistical analysis.
Prostate cancer is the second-leading cause of cancer-related deaths in men in the United States. Unfortunately, there is no effective therapy when prostate cancer becomes metastatic and refractory to conventional treatments. For this reason, the identification and exploration of new agents that red
Two-dimensional electrophoresis of prostatespecific antigen in sera of men with prostate cancer or benign prostate hyperplasia Prostate-specific antigen (PSA), the main marker for prostate cancer (PCa), is released from the prostate into the blood stream at nanogram level and may increase in PCa and