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Expression of p53 and p21waf1/cip1in gastric carcinoma: lack of inter-relationship or correlation with prognosis

โœ Scribed by PV Kaye; K Radebold; S Isaacs; DM Dent


Book ID
117817486
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
73 KB
Volume
26
Category
Article
ISSN
0748-7983

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p21WAF1/CIP1 expression in colorectal ca
โœ Viale, Giuseppe; Pellegrini, Caterina; Mazzarol, Giovanni; Maisonneuve, Patrick; ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 221 KB ๐Ÿ‘ 3 views

Defects in the mechanisms controlling the cell cycle are crucial in cell transformation and/or tumour progression. p21 WAF1/CIP1 is an inhibitor of cyclin-dependent kinases, induced by p53-dependent and p53-independent pathways, which can block progression through the cell cycle. p21 WAF1/CIP1 expre