## Abstract Microfracture is frequently used to repair articular cartilage defects and allows mesenchymal progenitors to migrate from subchondral bone into the defect and form cartilaginous repair tissue. The aim of our study was to analyze the cell surface antigen pattern and the differentiation c
Expression of osterix inhibits bone morphogenetic protein-induced chondrogenic differentiation of mesenchymal progenitor cells
β Scribed by Hiroyuki Tominaga; Shingo Maeda; Hiroyuki Miyoshi; Kohei Miyazono; Setsuro Komiya; Takeshi Imamura
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 613 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0914-8779
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Bone marrowβderived mesenchymal stem cells (MSC) are multipotent, selfβrenewing, mesodermalβorigin stem cells that are sequestered in the endosteal compartment. MSC are maintained in a relative state of quiescence in vivo but in response to a variety of physiological and pathological st
## Abstract Efficacious bone regeneration could revolutionize the clinical management of many bone and musculoskeletal disorders. Bone morphogenetic proteins (BMPs) can regulate the differentiation of mesenchymal stem cells into cartilage, bone, tendon/ligament, and fat lineages. Early data documen
This study rcports that recombinant adenovirus-mediated human bone morphogenetic protein-2 gene transfer can induce mesenchymal progenitor cell dillerentialion and bone formation. The recombinant adenovirus with the human hone morphogenetic protein-2 gene was constructed, and mature human bone morph