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Expression of nuclear hormone receptors in Escherichia coli

✍ Scribed by Danuta E Mossakowska

Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
300 KB
Volume
9
Category
Article
ISSN
0958-1669

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✦ Synopsis

Expression of nuclear hormone receptors in

Escherichia coil Danuta E Mossakowska Nuclear hormone receptors are ligand-activated transcription factors. The study of nuclear hormone receptor-ligand interactions requires expression of soluble receptor, but the production of functional soluble receptors in E. coil has generally proved difficult. Recent studies on coexpression of nuclear hormone receptors have yielded active soluble proteins, which were not readily generated when expressed individually.

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