Expression of N-myristoyltransferase in Human Brain Tumors
β Scribed by Yanjie Lu; Ponniah Selvakumar; Kaiser Ali; Anuraag Shrivastav; Gagan Bajaj; Lothar Resch; Robert Griebel; Daryl Fourney; Kotoo Meguro; Rajendra K Sharma
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 114 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0364-3190
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## BACKGROUND. Activated Src, which has intrinsic protein tyrosine kinase activity, has been found in human solid tumors such as colorectal and breast carcinomas. The Src gene encodes a cytoplasmic tyrosine kinase p60 src , which attaches to the inner surface of the membrane after N-terminal myris
## Abstract Matrix metalloproteinases (MMP) which degrades protein components of the extraβcellular matrix and basement membrane seems to be largely involved in cancer invasiveness. MMP proteolitic activity essentially comes from stromal cells but matrilysin (MMPβ7) is produced by the tumor itself.
Expression of mRNA for the 5 somatostatin receptors (sst 1-5 ) was characterized by Northern blot and RT-PCR analysis in 20 meningioma and 9 glioma samples. sst 1 mRNA was detectable by Northern blots of poly-A Ψ RNA in meningiomas but not gliomas. In contrast, sst 2 mRNA was readily detected by Nor
We have previously shown that aB-crystallin is a heat-shock protein which specifically accumulates in response to the expression of c-Ha-ras and v-mos oncogenes in mouse NIH 3T3 fibroblasts. Elevated levels of aB-crystallin mRNA or protein were shown to be associated with pathological conditions of