Many heterologous polypeptides fail to fold into their native state when expressed in Escherichia co~i; instead, they are either degraded by the cellular proteolytic machinery or accumulate in insoluble form, typically as inclusion bodies. Misfolding is a particularly vexing problem in the expressio
β¦ LIBER β¦
Expression of N-formylated proteins in Escherichia coli
β Scribed by Shari Spector; Julia M Flynn; Bruce Tidor; Tania A Baker; Robert T Sauer
- Book ID
- 116827712
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 196 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1046-5928
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