RAS gene mutations in childhood acute my
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Dr. Bert Vogelstein; Dr. Curt I. Civin; Antonette C. Preisinger; Jeffrey P. Kris
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Article
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1990
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John Wiley and Sons
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English
⚖ 336 KB
Mutations at codon I 2, I 3, and 6 I of the HRAS, KRAS, and NRASgenes were evaluated in 99 cases of pediatric acute myeloid leukemia (AML) using oligonucleotide hybridization to polymerase chain reacted derived products. Twenty-four mutations were identified in the NRAS gene, I 3 in the KRAS gene, a