Expression of Myelin Glycolipids and Proteins in Mitotic and Postmitotic Murine Oligodendrocytes
β Scribed by P. E. KNAPP; R. P. SKOFF
- Book ID
- 119865444
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 174 KB
- Volume
- 633
- Category
- Article
- ISSN
- 0890-6564
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Myelin membranes purified from mouse and rat brain are associated with alpha subunits of four signal transducing guanosine triphosphate (CTP)binding proteins: Go, Gi, G,, and ras. Four low-molecular-weight (M,) GTP-binding proteins are also present, as demonstrated by the binding of GTP to proteins
## Abstract We have shown previously that myelinβforming oligodendrocytes express the protein tyrosine phosphatase SHPβ1 and that myelin formation was decreased in SHPβ1βdeficient motheaten mice compared to that in normal littermates. These studies suggested a potential importance for SHPβ1 in olig
## Abstract The myelin basic protein (MBP) gene produces two families of proteins, the classic MBPs, important for myelination of the CNS, and the golli proteins, whose biological role in oligodendrocytes (OLs) is still unknown. The goals of this work were to study the in vitro pattern of expressio