Expression of MUC1 and MUC2 Mucins in Gastric Carcinomas: Their Relationship with Clinicopathologic Parameters and Prognosis
✍ Scribed by Nalan Akyürek; Gülen Akyol; Ayşe Dursun; Deniz Yamaç; Nazan Günel
- Book ID
- 111731608
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 625 KB
- Volume
- 198
- Category
- Article
- ISSN
- 0344-0338
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## BACKGROUND. Although mucin expressions appear to be correlated with prognoses in patients with various cancers, several studies have reported conflicting and inconclusive results on the prognostic significance of mucin expression in gastric carcinomas. ## METHODS. To clarify the correlations
Using 2 anti-mucin 1 (MUC1) monoclonal antibodies (MAbs), DF3 and BCP8, we examined MUC1 expression immunohistochemically in 192 esophageal squamous-cell carcinomas (SCCs). In normal squamous epithelium of the esophagus, DF3 was not expressed, but BCP8 was expressed on the cell membrane, mainly in t