Expression of MUC1 and MUC2 mucins in extrahepatic bile duct carcinomas: Its relationship with tumor progression and prognosis
β Scribed by Shugo Tamada; Masamichi Goto; Mitsuharu Nomoto; Koji Nagata; Takeshi Shimizu; Sadao Tanaka; Koro Sakoda; Kohzo Imai; Suguru Yonezawa
- Book ID
- 114431204
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 927 KB
- Volume
- 52
- Category
- Article
- ISSN
- 1320-5463
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Our previous immunohistochemical study on intrahepatic bile duct tumors showed that invasive cholangiocarcinoma (ICC) with a poor outcome expressed MUC1 mucin but was negative for MUC2 mucin, whereas bile duct cystadenocarcinoma (BDCC) with a favorable outcome was MUC1 negative and MUC2 positive. In
Using 2 anti-mucin 1 (MUC1) monoclonal antibodies (MAbs), DF3 and BCP8, we examined MUC1 expression immunohistochemically in 192 esophageal squamous-cell carcinomas (SCCs). In normal squamous epithelium of the esophagus, DF3 was not expressed, but BCP8 was expressed on the cell membrane, mainly in t