Expression of mTert in primary murine cells links the growth-promoting effects of telomerase to transforming growth factor-β signaling
✍ Scribed by Geserick, C; Tejera, A; González-Suárez, E; Klatt, P; Blasco, M A
- Book ID
- 110070485
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 298 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Smad proteins activated by TGF- form complexes with Smad4. Upon activation, these complexes translocate to the nucleus of the cell, where they induce transcription of genes related to inhibition of cell growth, cell differentiation and apoptosis. We investigated the role of Smads in the TGF-mediat
The relationship between the expression of selected oncogenes having different modes of action and the loss of the capacity t o respond in vitro to transforming growth factor+ I (TGF-P I) was analyzed in human mammary epithelial cells (MEC). Primary MEC cultures from healthy donors and the spontaneo