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Expression of melanoma-associated-antigens (MAAs), HLA I & II and of lymphocyte markers in biopsies of metastatic and primary melanoma

✍ Scribed by Lotem, M.; Abramovici, A.; Roizman, P.; Sulkes, A.; Schachter, J.; Adler, A.


Book ID
122896932
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
174 KB
Volume
29
Category
Article
ISSN
0959-8049

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MART-1/MelanA and Pmel17/gp100 are melanoma-associated antigens (MAAs) that can be recognized by tumorinfiltrating lymphocytes (TILs) capable of mediating successful adoptive therapy in vivo. Analysis of melanoma cell lines in vitro has demonstrated that heterogeneous antigen expression in the conte