Expression of matrix metalloproteinase-2 in glial and neuronal tumor cell lines: inverse correlation with proliferation rate
โ Scribed by Michael Thier; Elke Roeb; Bettina Breuer; Thomas A Bayer; Hartmut Halfter; J Weis
- Book ID
- 117469708
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 242 KB
- Volume
- 149
- Category
- Article
- ISSN
- 0304-3835
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๐ SIMILAR VOLUMES
Matrix metalloproteinase 2 (MMP-2) plays a crucial role in invasion and metastasis of malignant tumors. Membrane type 1-MMP (MT1-MMP) was originally identified as an activator of MMP-2. Tissue inhibitor of MMP-2 (TIMP-2) was identified as an inhibitor of MMP-2 and MT1-MMP. However, TIMP-2 was report
## Abstract ## BACKGROUND A distinction between noninvasive, invasive, and metastatic thymoma on the basis of the cytologic features is difficult. The current study investigated whether the expression of MMP and TIMP was correlated with tumor invasiveness and prognosis in patients with thymoma. #