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Expression of insulin receptor substrate-1 in hepatic diseases

✍ Scribed by Furusaka, Akihiro; Nagayama, Kazuo; Nishiyama, Masaki; Tanaka, Teruji

Book ID
122670905
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
163 KB
Volume
114
Category
Article
ISSN
0016-5085

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## Abstract The insulin receptor substrate‐1 (IRS‐1), a docking protein of the type 1 insulin‐like growth factor receptor (IGF‐IR) plays a significant role in cell proliferation and differentiation. The expression of IRS‐1 is down‐regulated in mouse embryo fibroblasts (MEFs) with a deletion of cave