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Expression of human proteoglycan in Chinese hamster ovary cells inhibits cell proliferation

✍ Scribed by Yamaguchi, Yu; Ruoslahti, Erkki

Book ID
109757024
Publisher
Nature Publishing Group
Year
1988
Tongue
English
Weight
501 KB
Volume
336
Category
Article
ISSN
0028-0836

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## Abstract Metallothionein (MT) gene expression is increased in cadmium resistant Chinese hamster ovary cells (CHO Cd^R^) upon medium (regular or serum‐free) change during culturing. Among the major components of the medium, NaHCO~3~ was found to be able to induce MT gene expression in a dose‐ and