4966843 Expression of interferon genes in Chinese hamster ovary cells
✍ Scribed by Prospéro-García, Oscar; Ott, Tilmann; Drucker-Colín, René
- Book ID
- 122412769
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 62 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0734-9750
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## Abstract In an effort to develop robust Chinese Hamster Ovary host cell lines, a variety of anti‐apoptotic genes were over‐expressed, either singly or in combination, followed by screening of transfectants for improved cell growth, extended longevity, reduced caspase 3/7 activity, and enhanced m
## Abstract Metallothionein (MT) gene expression is increased in cadmium resistant Chinese hamster ovary cells (CHO Cd^R^) upon medium (regular or serum‐free) change during culturing. Among the major components of the medium, NaHCO~3~ was found to be able to induce MT gene expression in a dose‐ and