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Expression of human phenylalanine hydroxylase activity in T lymphocytes of classical phenylketonuria children by retroviral-mediated gene transfer

✍ Scribed by C.M. Lin; Y. Tan; Y.M. Lee; C.C. Chang; K.J. Hsiao


Book ID
110222561
Publisher
Springer
Year
1997
Tongue
English
Weight
108 KB
Volume
20
Category
Article
ISSN
0141-8955

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## Abstract Human T‐lymphocytes are long lived, easily accessible, mature, and capable of proliferation. They are theoretically a suitable target for retroviral mediated gene transfer. To test this hypothesis, normal human T‐cells obtained from bone marrow and peripheral blood were stimulated with