Expression of Human Papillomavirus Type 16 Major Capsid Protein L1 in TransgenicArabidopsis thaliana
✍ Scribed by Sonia M’hirsi El Adab; Aymen Ezzine; Iness Ben Khedija; Lotfi Chouchane; Mohamed Nejib Marzouki
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 221 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0735-9640
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Human papillomavirus 6 (HPV 6) causes benign condylomata. As a model for HPV vaccine development, we tested a HPV 6 DNA vaccine candidate, constructed by subcloning the major capsid protein (L1) gene into an expression plasmid having the cytomegalovirus promoter, for its immunogenicity in BALB/c mic
The aim of this study was to further characterize the conformational neutralizing epitopes present on the surface-exposed FG loop of human papillomavirus (HPV) type 16 L1 major capsid protein. We have generated previously two chimeric L1 proteins by insertion of a foreign peptide encoding an epitope