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Expression of hCG/LH receptor gene and its functional coupling to the regulation of cyclooxygenase-1 and -2 enzymes in human fetal membranes

✍ Scribed by P. Toth; X. Li; Ch.V. Rao


Book ID
117315464
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
73 KB
Volume
14
Category
Article
ISSN
0143-4004

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In a recent communication, we demonstrated that prostaglandin E 2 (PGE 2 ) lowers basal while it ablates interleukin-1␀( (IL-1␀) and transforming growth factor-␀ (TGF␀) upregulated lysyl oxidase (LO) mRNA levels. Correspondingly, PGE 2 increases cyclooxygenase-1 (COX1) mRNA in diploid, human embryo