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Expression of GLUT-1 in psoriasis and the relationship between GLUT-1 upregulation induced by hypoxia and proliferation of keratinocyte growth

✍ Scribed by Tao, Juan; Yang, Jing; Wang, Lin; Li, Yan; Liu, Ye-Qiang; Dong, Jing; Li, Li; Wen, Xue; Shen, Guan-Xin; Tu, Ya-Ting


Book ID
119293380
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
790 KB
Volume
51
Category
Article
ISSN
0923-1811

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## Abstract The presence of hypoxia in tumours results in the overexpression of certain genes, which are controlled via the transcription factor HIF‐1. Hypoxic cells are known to be radioresistant and chemoresistant, thus, a reliable surrogate marker of hypoxia is desirable to ensure that treatment