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GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: relationship with vascularity and proliferation as predictors of outcome of ARCON

โœ Scribed by Hoskin, P J; Sibtain, A; Daley, F M; Wilson, G D


Book ID
109997756
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
346 KB
Volume
89
Category
Article
ISSN
0007-0920

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GLUT-1 and CAIX as intrinsic markers of
โœ Rachel E. Airley; Juliette Loncaster; James A. Raleigh; Adrian L. Harris; Susan ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 255 KB

## Abstract The presence of hypoxia in tumours results in the overexpression of certain genes, which are controlled via the transcription factor HIFโ€1. Hypoxic cells are known to be radioresistant and chemoresistant, thus, a reliable surrogate marker of hypoxia is desirable to ensure that treatment