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Expression of functional single-chain variable domain fragment (scFv) antibody against Metolcarb inPichia pastoris

โœ Scribed by Feng Cai, Tiejun Li, Yangang Xie, Xiaochun He

Book ID
120716338
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
387 KB
Volume
64
Category
Article
ISSN
1590-4261

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## Background The ability of cytosine deaminase (CD) to convert the antifungal agent 5-fluorocytosine (5-FC) into one of the most potent and largely used anticancer compound such as 5-fluorouracil (5-FU) raised considerable interest in this enzyme to model gene or antibody โ€“ directed enzyme-prodrug