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Characterization of a single-chain variable fragment (scFv) antibody directed against the human asialoglycoprotein receptor

โœ Scribed by Limin Cao; Guanxin Shen; Yinchang Zhu; Weiyu Wang; Xiaorong Zhao; Qing Ye; Huifen Zhu; Zhixian Lu; Jin Si


Book ID
111718082
Publisher
Portland Press
Year
2006
Tongue
English
Weight
521 KB
Volume
44
Category
Article
ISSN
0885-4513

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## Background The ability of cytosine deaminase (CD) to convert the antifungal agent 5-fluorocytosine (5-FC) into one of the most potent and largely used anticancer compound such as 5-fluorouracil (5-FU) raised considerable interest in this enzyme to model gene or antibody โ€“ directed enzyme-prodrug