Generation and characterization of a hum
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Alessandra Mallano; Silvia Zamboni; Giulia Carpinelli; Filippo Santoro; Michela
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Article
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2008
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BioMed Central
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English
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## Background The ability of cytosine deaminase (CD) to convert the antifungal agent 5-fluorocytosine (5-FC) into one of the most potent and largely used anticancer compound such as 5-fluorouracil (5-FU) raised considerable interest in this enzyme to model gene or antibody โ directed enzyme-prodrug