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Expression of epileptiform activity via nmda-receptor activation in slice cultures of the rat hippocampus

โœ Scribed by Sakaguchi, Takuya; Shin, Cheolsu; McNamara, James O.


Book ID
123108107
Publisher
Elsevier Science
Year
1991
Weight
83 KB
Volume
14
Category
Article
ISSN
0921-8696

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The pattern of epileptiform activity recorded from a number of in vitro seizure models is age dependent: ictal discharges are observed in immature brain slices while interictal bursts are seen in adult brain slices. This study evaluated the involvement of the N-methyl-D-aspartate (NMDA) receptor in