Expression of eIF4E During Head and Neck Tumorigenesis: Possible Role in Angiogenesis
β Scribed by Cherie-Ann O. Nathan; Scott Franklin; Fleurette W. Abreo; Raja Nassar; Arrigo de Benedetti; J. Williams; Fred J. Stucker
- Book ID
- 110082043
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 825 KB
- Volume
- 109
- Category
- Article
- ISSN
- 0023-852X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Objectives/Hypothesis: The eukaryotic translation initiation factor 4E (eIF4E) in conjunction with its binding protein, 4EBP1, regulates the translation of capβdependent mRNAs. An aberrant increase in eIF4E shifts the balance in favor of translation of transcripts that promote cell
## Abstract A new class of regulatory molecules known as microRNAs (miRNAs) is redefining our understanding of the molecular pathways associated with tumorigenesis. These miRNAs are small noncoding RNA (ncRNA) sequences with potent regulatory potential. The aberrant expression of miRNAs has been as