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Expression of dentin matrix protein 1 (DMP1) during fracture healing

✍ Scribed by S Toyosawa; N Kanatani; S Shintani; M Kobata; M Yuki; M Kishino; N Ijuhin; T Komori


Book ID
116318933
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
757 KB
Volume
35
Category
Article
ISSN
8756-3282

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## Abstract In this study, we investigated the effect of type I collagen on dentin matrix protein‐1 (Dmp‐1) and osteocalcin (OCN) gene expression of dental pulp cells. The mRNA level of Dmp‐1 gene was down‐regulated; however, OCN gene expression was up‐regulated by the culture of dental pulp cells

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## Abstract DMP1 is an acidic phosphorylated protein with the spatial and temporal expression that is largely restricted to bone and tooth tissues. The biological function of DMP1 is associated with biomineralization of bone, cartilage and tooth development. To study the cell‐specific expression of