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EXPRESSION OF CYTOCHROMES P450, CONJUGATING ENZYMES AND NUCLEAR RECEPTORS IN HUMAN HEPATOMA HepaRG CELLS

✍ Scribed by Aninat, C.


Book ID
118136805
Publisher
American Society for Pharmacology and Experimental Therapeutics
Year
2005
Tongue
English
Weight
533 KB
Volume
34
Category
Article
ISSN
0090-9556

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The aim of this study was to test suitable culture conditions for maintaining normal cellular cytoarchitecture and inducibility of P450 enzymes in primary cultures of human hepatocytes by prototypical inducers. The selectivity and sensitivity of a sandwich culture system were determined by treating