Expression of CYP2S1 in human hepatic stellate cells
β Scribed by Carylyn J. Marek; Steven J. Tucker; Matthew Koruth; Karen Wallace; Matthew C. Wright
- Book ID
- 118442226
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 383 KB
- Volume
- 581
- Category
- Article
- ISSN
- 0014-5793
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## Abstract We report a comprehensive examination of rat hepatic CYP1A2 and CYP2E1 ontogeny. We compare the data to human data to determine the rat's capacity as a model to identify CYPβmediated mechanisms underlying ageβdependent differences in susceptibility to toxicity. We evaluated CYP expressi
The hepatic stellate cell (HSC), following a fibrogenic stim-The hepatic stellate cell (HSC), following a fibrogenic ulus, undergoes an activation process in which changes occur stimulus, is transformed from a quiescent to an actiin cellular morphology, cellular metabolism, and in the patvated cell.