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CYP2E1-mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells

✍ Scribed by Natalia Nieto; Scott L. Friedman; Patricia Greenwel; Arthur I. Cederbaum

Book ID
118283784
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
311 KB
Volume
30
Category
Article
ISSN
0270-9139

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## Abstract Leptin is a 16‐kDa hormone with an array of biologic actions. We, and others, have demonstrated that leptin is critical to the development of liver fibrogenesis both in vitro and in the lean littermates of __ob__/__ob__ mice exposed to carbon tetrachloride (CCl~4~). Controversy exists a