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Expression of cyclooxygenase-2 (COX-2) in an advanced metastasized hypopharyngeal carcinoma and cultured tumor cells

✍ Scribed by Martin Scheer; Uta Drebber; Kai Breuhahn; Christoph Möckel; Tobias Reuther; Michael Kern; Joachim E. Zöller

Book ID
106241954
Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
318 KB
Volume
14
Category
Article
ISSN
1865-1550

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## Abstract ## BACKGROUND Cyclooxygenase‐2 (COX‐2) seems to be involved at various steps in the processes of malignant transformation and tumor progression. Investigations have shown that COX‐2 overexpression is associated with increased proliferation, reduced apoptosis, and angiogenesis. ## METH