Expression of CD38 on CD8 T cells predicts maintenance of high viraemia in HAART-treated HIV-1-infected children
β Scribed by Alessandra Vigano; Marina Saresella; Stefano Rusconi; Pasquale Ferrante; Mario Clerici
- Book ID
- 117288181
- Publisher
- The Lancet
- Year
- 1998
- Tongue
- English
- Weight
- 51 KB
- Volume
- 352
- Category
- Article
- ISSN
- 0140-6736
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For some membrane-associated antigens, the number of molecules expressed per cell carries information about the cell's differentiation and activation state. Quantitating antigen expression by flow cytometry has immediate application in monitoring CD38 expression on CD8 Ψ T cells in human immunodefic
## Abstract Excessive immune activation is a hallmark of chronic uncontrolled HIV infection. During the past years, growing evidence suggests that immune inhibitory signals also play an important role in progressive disease. However, the relationship between positive and negative immune signals on