Relevance of CD38 Expression on CD8 T Cells to Evaluate Antiretroviral Therapy Response in HIV-1-infected Youths
β Scribed by R. Rosso; D. Fenoglio; M. P. Terranova; F. Lantieri; D. Risso; E. Pontali; M. Setti; A. Cossarizza; J. L. Ravetti; C. Viscoli; A. Kunkl
- Book ID
- 110861860
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 123 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0300-9475
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For some membrane-associated antigens, the number of molecules expressed per cell carries information about the cell's differentiation and activation state. Quantitating antigen expression by flow cytometry has immediate application in monitoring CD38 expression on CD8 Ψ T cells in human immunodefic
## Abstract Excessive immune activation is a hallmark of chronic uncontrolled HIV infection. During the past years, growing evidence suggests that immune inhibitory signals also play an important role in progressive disease. However, the relationship between positive and negative immune signals on