Expression of Bcl-2, Bcl-XL, Bax and Apoptotic Index in Canine Mammary Tumours: Correlation with Clinicopathological Factlors
β Scribed by Yildirim, F.; Sonmez, K.; Ozyogurtcu, H.; Sennazli, G.; Gurel, A.; Gunduz, M.C.; Sontas, H.B.
- Book ID
- 122232555
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 63 KB
- Volume
- 150
- Category
- Article
- ISSN
- 0021-9975
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
In the present study, the prognostic impact of factors involved in the apoptosis pathway were tested on 67 consecutive patients treated with surgical resection. Included in the study were all patients resected for pancreatic adenocarcinoma from 1988 to 2003. Expression analysis for p53, Bax, and Bcl
Bcl-2 is a proto-oncogene which is involved in prolonging cell survival by inhibiting programmed cell death. Bax and bcl-x are members of the bcl-2 family; when overexpressed, they can counteract the ability of bcl-2 to inhibit apoptosis. This suggests a model in which the ratios of bcl-2 to bax and