Expression of AIDS virus envelope gene in recombinant vaccinia viruses
โ Scribed by Hu, Shiu-Lok; Kosowski, Steve G.; Dalrymple, Joel M.
- Book ID
- 109743312
- Publisher
- Nature Publishing Group
- Year
- 1986
- Tongue
- English
- Weight
- 486 KB
- Volume
- 320
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/320537a0
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## Abstract Two groups of 3 rabbits each were immunized with either recombinant vaccinia virus, WRโSFB5env, carrying the human Tโcell lymphotropic virus type I (HTLVโ1) __env__ gene at the site of the hemagglutinin gene of the WR strain, or control vaccinia virus, HAโWR, lacking the functional hema
Two types of recombinant vaccinia viruses (VVs) expressing the env gene of the human T-cell leukemia virus type I (HTLV-I) were reported previously. One recombinant VV, WR-proenv1, synthesized the authentic env protein. In the other recombinant VV, WR-env17, the env gene was inserted within the sign