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Expression of activation-induced cytidine deaminase decreases throughout the life

✍ Scribed by D. L. Radu; T. Kodera; C. Bona


Book ID
114778036
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2003
Tongue
English
Weight
173 KB
Volume
7
Category
Article
ISSN
1582-1838

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## Abstract Activation‐induced cytidine deaminase (AID) plays a role as a genome mutator in activated B cells, and inappropriate expression of AID has been implicated in the immunopathological phenotype of human B‐cell malignancies. Notably, we found that the transgenic mice overexpressing AID deve