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Cloning and expression of activation induced cytidine deaminase from Bos taurus

✍ Scribed by Subhash Verma; Tom Goldammer; Robert Aitken

Book ID
116966615
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
497 KB
Volume
134
Category
Article
ISSN
0165-2427

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## Abstract Activation‐induced cytidine deaminase (AID) plays a role as a genome mutator in activated B cells, and inappropriate expression of AID has been implicated in the immunopathological phenotype of human B‐cell malignancies. Notably, we found that the transgenic mice overexpressing AID deve