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Expression of a putative human mismatch repair gene MED1 in small cell lung cancer cell lines

✍ Scribed by Hansen, L.R; Spang-Thomsen, M; Petersen, L.N

Book ID
118570221
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
114 KB
Volume
29
Category
Article
ISSN
0169-5002

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## Abstract Although most advanced cancers are incurable, the majority of testicular germ cell tumors can be cured using cisplatin‐based combination chemotherapy. The nucleotide excision repair (NER) pathway removes most DNA adducts produced by cisplatin, and the low levels of NER in testis tumor c