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Expression of a normal and variant Alzheimer's β-protein gene in amyloid of hereditary cerebral hemorrhage, Dutch type: DNA and protein diagnostic assays

✍ Scribed by Frances Prelli; Efrat Levy; Sjoerd G. van Duinen; Gerard Th.A.M. Bots; Willem Luyendijk; Blas Frangione

Book ID
115763247
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
677 KB
Volume
170
Category
Article
ISSN
0006-291X

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## Abstract The amyloid β‐protein is a 39‐42 amino acid peptide that is deposited in senile plaques and in cerebral vessel walls in individuals with Alzheimer's disease, Down's syndrome, hereditary cerebral hemorrhage with amyloidosis–Dutch type (HCHW A‐D), and, to a much lesser extent, normal agin