Adrenal gland involvement in the regulat
✍
Marisa Laura Zallocchi; Laura Matkovic; Juan Carlos Calvo; María Cristina Damasc
📂
Article
📅
2004
🏛
John Wiley and Sons
🌐
English
⚖ 198 KB
## Abstract Renal 11β‐hydroxysteroid dehydrogenase 2 (HSD2) catalyzes the conversion of active glucocorticoids to inert 11β‐keto compounds, thereby preventing the illicit binding of these hormones to mineralocorticoid receptors (MRs) and, thus, conferring aldosterone specificity. Absence or inhibit