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Expression level of Wilms tumor 1 (WT1) protein has limited prognostic value in epithelial ovarian cancer From the Danish “MALOVA” Ovarian Cancer Study

✍ Scribed by Estrid V.S. Høgdall; Lise Christensen; Susanne K. Kjaer; Jan Blaakaer; Ib Jarle Christensen; Simon Gayther; Ian J. Jacobs; Claus K. Høgdall

Book ID: 113961080
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 405 KB
Volume: 106
Category: Article
ISSN: 0090-8258
DOI: 10.1016/j.ygyno.2007.03.043

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## Abstract ## BACKGROUND The HER‐2 (Human Epidermal Growth factor receptor‐2, also known as c‐__erb__‐2/__neu__) protooncogene encodes a transmembrane receptor protein, __M__~r~ 185,000. Studies have shown that the HER‐2 oncogene is overexpressed in approximately 25–30% of ovarian carcinoma (OC)