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Expression in Escherichia coli of hepatitis B virus DNA sequences cloned in plasmid pBR322

✍ Scribed by Burrell, C. J.; Mackay, Patricia; Greenaway, P. J.; Hofschneider, P. H.; Murray, K.

Book ID
109713876
Publisher
Nature Publishing Group
Year
1979
Tongue
English
Weight
706 KB
Volume
279
Category
Article
ISSN
0028-0836

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Amplification of pBR322 plasmid DNA in E
Amplification of pBR322 plasmid DNA in Escherichia coli relA strains during batch and fed-batch fermentation
✍ Dr. K. H. Hofmann; P. Neubauer; Sabine Riethdorf; M. Hecker πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 298 KB

## Abstract Fermenter studies under batch and fed‐batch conditions were carried out to test the possibility of plasmid pBR322 production in large amounts by using __E. coli relA__ strains. High amplification rates of pBR322 plasmid DNA were observed in __E. coli__ CP79 (__relA__) and __E. coli__ CP