Expression and Regulation of Na-Dependent Pi Transport in Matrix Vesicles Produced by Osteoblast-like Cells
β Scribed by C. Montessuit; J.P. Bonjour; J. Caverzasio
- Book ID
- 112119446
- Publisher
- American Society for Bone and Mineral Research
- Year
- 2009
- Tongue
- English
- Weight
- 651 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0884-0431
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Ascorbic acid (AA) is an essential cofactor for osteoblast differentiation both in vivo and in vitro. Before it can function, this vitamin must be transported into cells via a specific Na / -dependent AA transporter. In this study, we examine the regulation of this transport activity by glucocortico
Osteoblast-like cells possess Na-dependent transporters which accumulate orthophosphate (Pi) from the extracellular medium. This may be important in bone formation. Here we describe parallel measurements of Pi uptake and cellular [Pi] in such cells from the rat (UMR 106-01 and UMR 106-06) and human
## Abstract Endothelinβ1 (ETβ1) has been reported to modulate bone metabolism both in vivo and in vitro. In the present study, we investigated the effect of ETβ1 on inorganic phosphate (Pi) transport in osteoblastβlike cells, which is now considered to be important for the initiation of bone matrix
Parathyroid hormone (PTH) receptors and the biological response to PTH in osteoblasts have been shown to be influenced by glucocorticoids, growth factors, cytokines or PTH itself. Furthermore, components of extracellular matrix (ECM) appear to regulate the response to PTH as well. We investigated th