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Expression and regulation mechanisms of Sonic Hedgehog in breast cancer

✍ Scribed by Wei Cui; Li-Hui Wang; Yuan-Yuan Wen; Min Song; Bai-Lin Li; Xiao-Ling Chen; Man Xu; Su-Xiang An; Jing Zhao; Yi-Yan Lu; Xiao-Yi Mi; En-Hua Wang


Book ID
108586663
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
531 KB
Volume
101
Category
Article
ISSN
1347-9032

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## Abstract Pancreatic cancer is an aggressive malignancy that exhibits a number of genetic and epigenetic alterations. Indian hedgehog (Ihh) and its 2 signaling receptors, patched (Ptc) and smoothened (Smo), are involved in pancreatic development and regulation of β‐cell function as well as in cer