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Expression and purification of phosphorylated and non-phosphorylated human MEK1

โœ Scribed by Catherine K. Smith; Donna Carr; Todd W. Mayhood; Weihong Jin; Kimberly Gray; William T. Windsor


Book ID
116828525
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
349 KB
Volume
52
Category
Article
ISSN
1046-5928

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## Abstract Grb7 is a member of the Grb7 family of proteins, which also includes Grb10 and Grb14. All three proteins have been found to be overexpressed in certain cancers and cancer cell lines. In particular, Grb7 (along with the receptor tyrosine kinase erbB2) is overexpressed in 20โ€“30% of breast